Method of purifying polypeptides by simulated moving bed...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) B01D 15/18 (2006.01) C07K 1/16 (2006.01)

Patent

CA 2498725

Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed ("SMB") system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the SMB methods and apparatus and methods of treatment with the purified immunoreactive compounds.

L'invention concerne des procédés de séparation d'un composé immunoréactif d'au moins un constituant immatériel, consistant à utiliser un système de lit mobile simulé (<= SMB >=) et un appareil SMB destiné à être utilisé dans ces procédés. L'invention concerne également des composés immunoréactifs purifiés préparés à l'aide des procédés et de l'appareil SMB ainsi que des méthodes de traitement utilisant les composés immunoréactifs purifiés.

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