Method of radio-sensitizing tumors using a radio-sensitizing...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/70 (2006.01) A61K 31/4035 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2671517

The present invention relates to a method of treating cancer using PARP inhibitors as radio-sensitization agents of tumors. Specifically the present invention relates to a method of radio-sensitization of tumors using a compound of Formula (I) or a pharmaceutically acceptable salt form thereof. The present invention also relates to a pharmaceutical compositions of PARP inhibitors for radiosensitizing tumors.

Cette invention concerne un procédé permettant de traiter le cancer en utilisant des inhibiteurs de PARP comme agents de radiosensibilisation des tumeurs. De manière spécifique, l'invention concerne un procédé de radiosensibilisation des tumeurs en utilisant un composé de formule (I) ou son sel pharmaceutiquement acceptable. L'invention concerne par ailleurs des compositions pharmaceutiques d'inhibiteurs de PARP destinées à radiosensibiliser les tumeurs.

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