Method of reducing mortality associated with congestive...

Details Method of reducing mortality associated with congestive... Method of reducing mortality associated with congestive...

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A61K 31/34 (2006.01) A61K 31/50 (2006.01) A61K 31/58 (2006.01) A61K 31/63 (2006.01) A61K 31/655 (2006.01)

Patent

CA 1308659

A METHOD OF REDUCING MORTALITY ASSOCIATED WITH CONGESTIVE HEART FAILURE USING HYDRALAZINE AND ISOSORBIDE DINITRATE Abstract of the Disclosure A method of reducing mortality associated with chronic congestive heart failure in a patient with impaired cardiac function and concomitant reduced exercise tolerance, comprising the oral administration to said patient in need of the same of a combination of (a) between about 75 and about 300 milligrams of hydralazine, per day and (b) between about 40 and about 160 milligrams of isosorbide dinitrate, per day.

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