Method of reducing neuronal injury or apoptosis

Details Method of reducing neuronal injury or apoptosis Method of reducing neuronal injury or apoptosis

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/00 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/506 (2006.01)

Patent

CA 2373883

The invention relates to a method of reducing neuronal injury or apoptosis including administering to a patient in need thereof an effective amount of a p38 mitogen-activated protein kinase (MAPK) inhibitor. Methods of treating an HIV-mediated dementia, glaucoma, or other neurodegenerative disorders are also disclosed.

L'invention concerne un procédé destiné à réduire une blessure neuronale ou empêcher l'apoptose. Le procédé consiste à administrer à un patient qui en a besoin une quantité effective d'un inhibiteur de la protéine kinase p38 activée par mitogène (MAPK). L'invention concerne également des procédés de traitement de la démence induite par le VIH, du glaucome, ou d'autres troubles neurodégénératifs.

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