Method of reducing side effects of isoniazid

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/675 (2006.01) A61K 31/4409 (2006.01)

Patent

CA 2590104

This invention relates to a method of reducing the side effects of isoniazid. Specifically, the invention relates to administration of pyridoxal 5'-phosphate to reduce or mitigate the side effects of isoniazid. Also provided is the use of pyridoxal 5'- phosphate in the preparation of a medicament for the reduction of the side effects of isoniazid, a pharmaceutical composition comprising isoniazid and pyridoxal 5'-phosphate, and kits comprising pyridoxal 5'-phosphate and instructions for use of same to combat the side effects of isoniazid.

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