Method of regulating immune function

A - Human Necessities – 61 – K

Patent

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A61K 31/13 (2006.01) A61K 31/00 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/166 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/445 (2006.01) A61K 31/4515 (2006.01) A61K 31/454 (2006.01) A61K 31/48 (2006.01) A61K 31/54 (2006.01) A61K 31/5415 (2006.01) A61K 38/22 (2006.01)

Patent

CA 2194501

Methods for rectifying or ameliorating abnormal responses of mammalian immune systems is provided. Also provided are methods for modifying normal responses of the mammalian immune system. Further provided is a method for treating a mammal having an immune dysfunction by administering to the mammal a prolactin reducer and/or enhancer at a predetermined time or times during a 24-hour period that results in modification of the mammal's abnormal prolactin profile so that it approaches or conforms to the prolactin profile of a young mammal of the same species, thereby ameliorating said immune dysfunction. Also provided is a method of upregulating or augmenting an immune response in a mammal.

On décrit des procédés permettant de corriger ou d'améliorer des réactions anormales des systèmes immunitaires chez des mammifères. On décrit aussi des procédés permettant de modifier des réactions normales de ces systèmes. On décrit en outre un procédé de traitement d'un mammifère souffrant d'un dysfonctionnement immunitaire qui consiste à administrer à ce dernier un agent réduisant et/ou augmentant le taux de prolactine à une ou des heures prédéterminées sur une période de 24 heures, ce qui modifie le profil de prolactine anormal de ce mammifère pour qu'il soit partiellement ou totalement conforme au profil de prolactine d'un jeune mammifère de même espèce et atténue donc ce dysfonctionnement immunitaire. On décrit enfin un procédé permettant d'accroître ou de renforcer une réaction immunitaire chez un mammifère.

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