C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/48 (2006.01) A61K 38/00 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12Q 1/54 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2589563
It is intended to provide a method of screening a compound which directly activates glycogen synthase; an isolated nucleic acid encoding a mutant of glycogen synthase (2); a vector having this nucleic acid inserted therein; this vector to be used in gene therapy; a mutant of glycogen synthase (2); and a remedy for diabetes which contains this mutant as the active ingredient.
Cette invention concerne un procédé de criblage d'un composé qui active directement la glycogène synthase; un acide nucléique isolé codant un mutant de la glycogène synthase (2); un vecteur dans lequel cet acide nucléique est inséré; ledit vecteur destiné à être utilisé en thérapie génique; un mutant de la glycogène synthase (2); et un médicament servant au traitement du diabète et contenant ce mutant comme ingrédient actif.
Eiki Jun-Ichi
Kadotani Akito
Nagata Yasufumi
Nakamura Takao
Suzuki Maho
Banyu Pharmaceutical Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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