G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2700875
The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein said screening method comprises a step which comprises determining whether the functional activity of a TASK-2 polypeptide in the presence of a test molecule is decreased or eliminated compared with the functional activity of said TASK-2 polypeptide in the absence of said test molecule, the test molecule being considered to be a candidate molecule when it decreases or eliminates said functional activity.
La présente invention se rapporte à l'utilisation d'un procédé de criblage pour l'identification de molécules candidates utilisables pour le traitement de troubles respiratoires chez un mammifère, ledit procédé de criblage comprenant une étape consistant à déterminer si l'activité fonctionnelle d'un polypeptide TASK-2 en présence d'une molécule test est diminuée ou supprimée par rapport à l'activité fonctionnelle dudit polypeptide TASK-2 en l'absence de ladite molécule test, la molécule test étant considérée comme étant une molécule candidate lorsqu'elle diminue ou supprime ladite activité fonctionnelle.
Barhanin Jacques
Gestreau Christian
Heitzmann Dirk
Thomas Jorg
Warth Richard
Centre National de La Recherche Scientifique-Cnrs
Smart & Biggar
Universite Paul Cezanne Marseille III
LandOfFree
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