Method of screening for large offspring syndrome

Details Method of screening for large offspring syndrome Method of screening for large offspring syndrome

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 31/18 (2006.01) C07K 14/72 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2344104

A method is provided for the diagnosis of Large Offspring Syndrome (LOS) in animals prepared by nuclear transfer or in animals prepared by methods of in vitro fertilisation or culture which comprises analysing Insulin-like growth factor-2 receptor (Igf2r) gene expression in the animal embryo or in a biological sample from the embryo.

La présente invention concerne une méthode de diagnostic du syndrome de surdéveloppement de l'embryon dans le cas d'animaux obtenus par transfert de noyau ou par des méthodes de fertilisation ou de culture in vitro. Cette méthode consiste à analyser l'expression du gène récepteur (Igf2r) du facteur 2 de croissance insuline-like chez l'embryon de l'animal ou dans un échantillon biologique de l'embryon.

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