Method of screening for target ligands

Details Method of screening for target ligands Method of screening for target ligands

C - Chemistry, Metallurgy

12

N

C12N 9/00 (2006.01) C12N 9/12 (2006.01) C12N 15/09 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2519361

A general system for screening targets (e.g., biomolecules) is described. The screening can be used to discover compounds that bind to a naturally occurring low activity or inactive state of a target and act as inhibitors of the target function as seen in subsequent biological assays.

L'invention concerne un système général de criblage de cibles (ex. des biomolécules). Le criblage peut être utilisé pour la découverte de composés qui se lient à une cible naturelle à l'état inactif ou faiblement active, et qui font office d'inhibiteurs de la fonction cible comme c'est le cas dans des essais biologiques ultérieurs.

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