Method of screening tgf-.beta. inhibiting substances

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/15 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2306778

A method of screening substances which inhibit the bonding of TAK1 polypeptide to TAB1 polypeptide, characterized by contacting TAK1 polypeptide and a sample with TAB1 polypeptide and detecting or determining the TAK1 polypeptide bonded to the TAB1 polypeptide.

La présente invention se rapporte à un procédé de sélection de substances ayant une action inhibitrice sur la liaison du polypeptide TAK1 au polypeptide TAB1, caractérisé en ce qu'il consiste à mettre en contact le polypeptide TAK1 et un échantillon avec le polypeptide TAB1, et à détecter ou déterminer le polypeptide TAK1 lié au polypeptide TAB1.

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