Method of seeding cells onto the surface of medical implants

Details Method of seeding cells onto the surface of medical implants Method of seeding cells onto the surface of medical implants

A - Human Necessities

61

L

A61L 27/38 (2006.01) A61F 2/02 (2006.01)

Patent

CA 2288532

To coat a surface of a medical implant such as an organ part or a synthetic prosthesis with a coating of living cells, the implant is inserted and fixed into a receiving container which is at least partially filled with a nutritive liquid medium containing the coating cells in suspension. Then the receiving container is rotated respectively about two distinct rotation axes, whereby preferably the two rotation motions are independently controllable and the two axes are substantially perpendicular to each other. Each of the two rotation motions can be a continuous rotation through 360°, or a stepwise intermittent rotation through successive rotational angle steps. The parameters of the two rotations about the two axes can be combined as needed for a particular application, for example a continuous rotation about one axis combined with a stepwise rotation about the other axis. The time period and rotational speed of each rotation can also be independently controlled. A uniform and complete coating of cells on all surfaces of the implant is achieved.

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