Method of selecting antioxidants for use in topically...

G - Physics – 01 – N

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G01N 33/50 (2006.01) A61K 8/37 (2006.01) A61K 8/67 (2006.01) A61K 8/97 (2006.01) A61Q 17/04 (2006.01)

Patent

CA 2711270

Antioxidant-containing compositions and methods for confirm-ing antioxidant activity of a composition formulated for topical application to skin. Methods for testing a composition for ability to inhibit both ultraviolet radia-tion-induced lipid peroxidation on skin and ultraviolet radiation-induced reactive oxygen species formation in the stratum corneum. Compositions and methods for treating and preventing photodamage to skin.

L'invention porte sur des compositions à teneur en antioxydant et sur des procédés pour confirmer l'activité antioxydante d'une composition formulée pour une application topique sur la peau. L'invention porte également sur des procédés pour analyser l'aptitude d'une composition à inhiber à la fois une peroxydation de lipides induite par un rayonnement ultraviolet sur la peau et une formation d'espèces à oxygène réactif induites par un rayonnement ultraviolet dans le stratum corneum, ainsi que sur des compositions et des procédés pour traiter et prévenir une photolésion de la peau.

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