Method of separating l-tryptophan

C - Chemistry – Metallurgy – 07 – D

Patent

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260/319.5

C07D 209/20 (2006.01) C12N 1/02 (2006.01) C12P 13/22 (2006.01)

Patent

CA 1215068

Abstract of the Disclosure When an L-tryptophan-containing reaction mixture produced by a reaction utilizing a micro- organism is adjusted to pH 2 to 5 with a mineral acid and then heated, the microorganism contained in the reaction mixture is flocculated. The flocculated microorganism is removed by either (1) filtering the reaction mixture, or (2) adding an alkali to the reaction mixture to convert L-tryptophan to its alkali salt and then filtering the mixture. L-tryptophan of high purity can be obtained from the filtrate.

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