Method of stabilizing preparation

A - Human Necessities – 61 – K

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Details

A61K 47/20 (2006.01) A61K 31/4709 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2408796

A method for stabilizing a preparation which comprises incorporating at least one member selected from the group consisting of natural salts, basic salts, and basic substances into a preparation containing a pharmacological substance and sodium lauryl sulfate. The thus-obtained preparation containing sodium lauryl sulfate has excellent storage stability, is inhibited from changing in color or deteriorating, and has excellent performances such as unsusceptibility to a change in properties, e.g., the rate of release of the pharmacological substance therefrom.

Procédé servant à stabiliser une préparation et consistant à incorporer au moins un constituant sélectionné dans le groupe constitué par des sels naturels, des sels basiques et des substances basiques dans une préparation contenant une substance pharmacologique et sulfate de sodium laurylé. La préparation obtenue contenant sulfate de sodium laurylé présente une stabilité excellente à la conservation, ne change pas de couleur ni ne se détériore et possède d'excellentes propriétés de conservation de, par exemple, la vitesse de libération de la substance pharmacologique qu'elle contient.

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