A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/21 (2006.01) A61K 47/00 (2006.01)
Patent
CA 2567309
A method of preparing a stabilized bulk solution of a monomeric protein is described, which consists in providing a bulk of monomeric protein in a buffer solution and adding an excipient to the bulk, wherein the excipient is selected from the group consisting of bacteriostatic agents, surfactants, isotonicity agents, amino acids, antioxidants and combinations thereof. Preferably the monomeric protein is IFN-beta.
L'invention porte sur un procédé de préparation d'une solution principale stabilisée d'une protéine monomère, consistant à fournir une quantité de protéine monomère dans une solution tampon et à ajouter un excipient dans la quantité, l'excipient étant choisi dans le groupe agents bactériostatiques, agents de surface, agents d'isotonicité, acides aminés, antioxydants et des combinaison de ceux-ci. De préférence, la protéine monomère est IFN-beta.
Ares Trading S.a.
Kirby Eades Gale Baker
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