Method of stabilizing urokinase precursor and dry...

Details Method of stabilizing urokinase precursor and dry... Method of stabilizing urokinase precursor and dry...

C - Chemistry, Metallurgy

12

N

195/39.1, 167/10

C12N 9/96 (2006.01) A61K 38/49 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) A61K 47/42 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336585

A method of stabilizing a urokinase precursor and a dry preparation containing said stabilized urokinase are disclosed. This method comprises adding, as stabilizers, (a) at least one member of inorganic salts, organic acid salts, and polar amino acids and the salts thereof, and (b) albumin to the urokianse precursor. The urokinase precursor-containing preparation is highly stable and can be stored for a long period of time.

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