Method of sterilizing

Details Method of sterilizing Method of sterilizing

A - Human Necessities

61

K

A61K 31/785 (2006.01) A01N 33/04 (2006.01) A01N 37/44 (2006.01) A23L 1/30 (2006.01) A61L 2/16 (2006.01) A61P 25/00 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2375237

A method of sterilizing objects as well as the sterilized objects obtained from the method are disclosed. The method involves contacting an object such as a medical device to be reused with polycationic dendrimer under conditions which result in rendering a conformationally altered protein (e.g. a prion) non-infectious. A disinfecting agent or surgical scrub composition which comprises the dendrimers is also disclosed as are gelatin capsules treated with polycationic dendrimers.

Cette invention a trait à une technique de stérilisation d'objets ainsi qu'aux objets stérilisés obtenus grâce à cette technique. Cette technique consiste à mettre un objet, un dispositif médical à réutiliser notamment, en contact avec un dendrimère cationique dans des conditions se soldant par l'obtention d'une protéine modifiée de façon conformationnelle non infectieuse (un prion, par exemple). L'invention concerne également un agent désinfectant ou une composition pour brossage chirurgical renfermant ces dendrimères, sous forme de capsules de gélatine traitées à l'aide desdits dendrimères.

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