A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
167/139
A61L 2/04 (2006.01) A61K 39/395 (2006.01) A61L 2/00 (2006.01)
Patent
CA 1306691
ABSTRACT OF THE DISCLOSURE A gamma-globulin aqueous solution can be subjected to sterile heat-treatment without loosing its activity when the treatment is conducted in the presence of at least one stabilizer of monosaccharide, disaccharide or sugar- alcohol added to the solution. The stabilizer effects to decrease the harmful polymer or anticomplement activity of the gamma-globulin before the treatment but to maintain the titer of a wide variety of antibodies to various viruses and bacteria, while the infectivity of viruses possibly contained is completely removed. Another stabilizer of a neutral amino and, a neutral inorganic salt, an organic carboxylic acid salt or a surface active agent assists the stabilizer when used together.
501859
Hirao Yutaka
Uemura Yahiro
Uriyu Katuhiro
Fetherstonhaugh & Co.
Mitsubishi Pharma Corporation
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