Method of treating abnormal cell growth using c-met and...

Details Method of treating abnormal cell growth using c-met and... Method of treating abnormal cell growth using c-met and...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2556025

The invention provides a method of treataing abnormal cell growth in a mammal, such as a human, by administering to the mammal a therapeutically effective amount of a c-MET inhibitor and a mammalian target of rapamycin (mTOR) inhibitor. Figure 1 shows PHA665752 inhibition of cell growth of TPR-MET transformed BaF3 cells.

L'invention concerne une méthode de traitement d'une croissance cellulaire anormale chez un mammifère, tel qu'un humain. Cette méthode consiste à administrer au mammifère une quantité thérapeutiquement efficace d'un inhibiteur c-MET et d'une cible mammifère d'inhibiteur rapamycine (mTOR). La figure 1 montre l'inhibition PHA665752 de la croissance de cellules BaF3 transformées par TPR-MET.

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