A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/423 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2555149
A method of treating or preventing Obstructive Sleep Apnea (OSA) comprises the administration of a pharmacologically effective amount of zonisamide to a patient in need thereof, with the proviso that OSA caused by external mechanical obstruction of the airways, such as by mucus, is excluded. Also disclosed is the use of zonisamide for the manufacture of a medicament useful in the treatment; a protective patch comprising zonisamide and a pharmaceutically acceptable carrier for transdermal or transmucosal administration to a person suffering from OSA; and the use of zonisamide for the manufacture of a diagnostic device, kit or composition for the diagnosis of sleep disordered breathing.
La présente invention a trait au traitement et à la prévention de l'apnée obstructive du sommeil comprenant l'administration d'une quantité pharmacologiquement efficace de zonisamide à un patient qui en a besoin, sauf si l'apnée obstructive du sommeil est provoquée par un obstruction mécanique des voies aériennes, tells que du mucus. L'invention a également trait à l'utilisation de zonisamide pour la fabrication d'un médicament utile dans le traitement ; à une bande adhésive comportant du zonisamide et un support pharmaceutiquement acceptable pour l'administration transdermique ou transmuqueuse à une personne souffrant de l'apnée obstructive du sommeil ; et l'utilisation du zonisamide pour la fabrication d'un dispositif, d'une trousse, d'une composition de diagnostic pour le diagnostic de la respiration irrégulière.
Grote Ludger
Hedner Jan
Stenlof Kaj
Grote Ludger
Hedner Jan
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Stenlof Kaj
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