Method of treating bladder and lower urinary tract syndromes

Details Method of treating bladder and lower urinary tract syndromes Method of treating bladder and lower urinary tract syndromes

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C07K 14/00 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2327543

The present invention relates to bladder and lower urinary tract syndromes, particularly, irrative symptoms, and to a method of treating same using .alpha.1d-adrenergic receptor (.alpha.1dAR) antagonists. The invention further relates to a method of screening compounds for their ability to serve as .alpha.1dAR selective antagonists.

La présente invention concerne les affections du bas appareil urinaire et de la vessie, notamment les symptômes d'irritation, ainsi qu'une méthode de traitement de ces affections faisant appel à des agonistes des récepteurs adrénergiques .alpha.¿1d? (.alpha.¿1d?AR). L'invention concerne également une méthode de criblage de composés en fonction de leur aptitude à être utilisés comme antagonistes sélectifs des .alpha.¿1d?AR.

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