A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2592971
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs, and in particular to the use of these compounds in treating brain cancer.
L'invention concerne des 4-arylamino-quinazolines et des analogues de ces dernières efficaces en tant qu'activateurs des caspases et en tant qu'inducteurs de l'apoptose. Les composés selon l'invention sont utilisés dans le traitement de divers états cliniques caractérisé par une croissance non contrôlé et une propagation de cellules anormales. D'une manière plus spécifique, l'invention concerne l'utilisation de ces composés dans le traitement du cancer du cerveau.
Anderson Mark B.
Cai Sui Xiong
Sirisoma Nilantha Sudath
Willardsen Adam
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cytovia Inc.
Myriad Genetics Inc.
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