Method of treating cachexia and certain new compounds for...

Details Method of treating cachexia and certain new compounds for... Method of treating cachexia and certain new compounds for...

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 487/14 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01)

Patent

CA 1329199

ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) [in which: Y represents a group of formula Image (III); the dotted line is a double or single bond; R1 is hydrogen, alkyl or aryl; R2 is hydrogen or halogen; R3 is alkyl or cycloalkyl; R4 is hydrogen, alkyl, hydroxy or halogen; R5 is hydrogen, alkyl. hydroxy, oxygen or halogen: and R6 is hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or aralkyl;] and pharmaceutically acceptable salts thereof are valuable in the treatment of cachexia. Certain of these compounds are novel.

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