Method of treating cancer by administration of 5-substituted...

A - Human Necessities – 61 – K

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Details

A61K 31/7068 (2006.01) A61K 31/7052 (2006.01) A61K 31/7072 (2006.01) A61K 33/24 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2601558

The invention relates to methods of administration of at least one overexpression inhibitor of DNA repair genes and/or oncogenes (e.g., (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU), or a prodrug, or salt thereof) to increase the cytotoxic effect of a cytostatic or cytotoxic chemotherapeutic agent during and/or after chemotherapy, e.g., in the treatment of cancer.

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