A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/40 (2006.01) A61K 31/00 (2006.01) A61K 31/341 (2006.01) A61K 31/5415 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01)
Patent
CA 2376179
The present invention relates to a method of ameliorating or preventing temporal progression of burning cutaneous erythema in a subject which method comprises administering to a subject in need thereof an effective amount of an H1 and/or H2 receptor antagonist. The present invention also relates to a method of treating colorectal carcinoma in a subject, the method comprising administering to the subject 30.6 antibody and an amount of an H1 and/or H2 receptor antagonist effective in reducing at least one adverse side effect associated with administration of an H1 and/or H2 receptor antagonist. The present invention further relates to a method of ameliorating or preventing at least one adverse side effect associated with the administration of 30.6 antibody to a subject, the method comprising administering an effective amount of an H1 and/or H2 receptor antagonist to the subject in conjunction with administration of the 30.6 antibody.
L'invention concerne une méthode permettant d'améliorer ou de prévenir la progression temporelle de l'érythème cutané chez un sujet. Cette méthode consiste à administrer à un sujet nécessitant un tel traitement une quantité efficace d'antagoniste du récepteur H1 et/ou H2. L'invention concerne également une méthode de traitement du cancer colorectal. Cette méthode consiste à administrer au sujet l'anticorps 30.6 et une quantité d'antagoniste du récepteur H1 et/ou H2 suffisante pour réduire au moins un effet secondaire associé à l'administration de l'anticorps 30.6. L'invention concerne en outre une méthode permettant d'améliorer ou de prévenir au moins un effet secondaire associé à l'administration de l'anticorps 30.6 chez un sujet. Cette méthode comprend l'administration d'une quantité efficace d'un antagoniste du récepteur H1 et/ou H2 conjointement à l'administration de l'anticorps 30.6.
Smith Glenn Martin
Ward Robyn Lynne
Crc For Biopharmaceutical Research Pty Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Smith Glenn Martin
Ward Robyn Lynne
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