Method of treating cardiac arrhythmia with 3-benzoyl-3,...

Details Method of treating cardiac arrhythmia with 3-benzoyl-3,... Method of treating cardiac arrhythmia with 3-benzoyl-3,...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 487/10 (2006.01)

Patent

CA 2141367

The use of 3-benzoyl-3,7-diazabicyclo[3.3.1] nonane compounds of the general formula I Image I in which R1 is an alkyl group having 1 - 6 carbon atoms or a cycloalkylalkyl group having 4 - 7 carbon atoms, R2 and R3 are each individually lower alkyl or together form an alkylene chain having 3 - 6 carbon atoms, R4 is hydrogen, halogen, cyano, nitro, trifluoromethyl or a R6-SO2- group, in which R6 is fluorine or lower alkyl, and R5 is hydrogen, halogen, trifluoromethyl or nitro, or their physiologically acceptable acid addition salts for the treatment of cardiac arrhythmias in larger mammals, including humans.

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