Method of treating chronic obstructive pulmonary disease

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2352543

A class of .OMEGA.-substituted(1,4-benzoquinon-2-yl)alkanoic acids are useful in the treatment of chronic obstructive pulmonary disease (COPD). The preferred compound for the method of treatment is 7-(3,5,6-trimethyl-1,4- benzoquinon-2-yl)-7-phenylheptanoic acid or a pharmaceutically acceptable salt, ester or pro-drug thereof.

Cette invention se rapporte à une classe d'acides [1,4-benzoquinon-2-yl]alcanoïques .OMEGA.-substitués, qui servent dans le traitement des bronchopneumopathies chroniques obstructives (BPCO). Le composé préféré pour ce procédé de traitement est l'acide-(3,5,6-triméthyl-1,4-benzoquinon-2-yl)-7-phénylheptanoïque ou un sel, ester ou promédicament de cet acide, acceptables sur le plan pharmaceutique.

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