Method of treating corneal transplant rejection

Details Method of treating corneal transplant rejection Method of treating corneal transplant rejection

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01) C07K 14/71 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2519835

Methods of preventing, reducing, or treating corneal transplant rejection to improve transplant survival in a subject in need thereof comprising administering an agent capable of blocking or inhibiting vascular endothelial growth factor (VEGF) are provided. The methods are useful for inhibiting or preventing corneal transplant rejection in a human subject who is the recipient of a transplanted cornea.

L'invention concerne des méthodes de prévention, de réduction ou de traitement du rejet de greffon cornéen, permettant d'améliorer la survie du greffon chez un sujet subissant une transplantation. Ces méthodes consistent à administrer un agent capable de bloquer ou d'inhiber le facteur de croissance endothéliale vasculaire (VEGF). Ces méthodes permettent d'inhiber ou de prévenir efficacement le rejet de greffon cornéen chez un sujet humain subissant une transplantation de la cornée.

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