A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 5/142 (2006.01) A61N 1/05 (2006.01) A61N 1/36 (2006.01) A61P 25/00 (2006.01) A61P 25/24 (2006.01)
Patent
CA 2432810
In one aspect there is provided a method of using one or more drugs to therapeutically treat depression, mood disorders and anxiety disorders by means of an implantable pump and a catheter having a proximal end coupled to the pump and a discharge portion for infusing therapeutic dosages of the one or more drugs, as well as an electric signal generator and an implantable electrode having a proximal end and a stimulation portion, the method comprising the steps of: surgically implanting the electrode so that the stimulation portion lies adjacent a predetermined stimulation site preferably selected from the group consisting of the Subcallosal Cingulate area 25, the Subcaudate area, and the orbitofrontal cortex areas in brain tissue, which site when electrically stimulated, reduces symptoms of depression, mood disorders and anxiety disorders; surgically implanting the catheter so that the discharge portion lies adjacent a predetermined infusion site preferably selected from the group consisting of the Subcallosal Cingulate area 25 and the orbitofrontal cortex areas in the brain tissue, which site when therapeutic dosages of the one or more drugs are infused thereto, reduces symptoms of depression, mood disorders and anxiety disorders; coupling the proximal end of the electrode to the signal generator; operating the signal generator to stimulate the stimulation site; operating the pump to discharge a predetermined dosage of the one or more drugs through the discharge portion of the catheter into the infusion site while the signal generator is stimulating the stimulation site, whereby depression, mood disorders and anxiety disorders are treated.
Lozano Andres M.
Mayberg Helen S.
Advanced Neuromodulation Systems Inc.
Borden Ladner Gervais Llp
Lozano Andres M.
Mayberg Helen S.
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