A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/495 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2486712
Methods comprising the administration of a partial fatty acid oxidation inhibitor such as ranolazine are provided for treating diabetes, lowering plasma level of HbAlc, gluclose plasma levels, total cholesterol levels and delaying onset of diabetic retinopathy in a diabetic, pre-diabetic, or a non- diabetic mammal while minimizing undesirable side effects.
La présente invention a trait à des procédés de traitement du diabète, de réduction de la concentration plasmique d'hémoglobine glycosylée, de taux de glucose plasmatique, de niveau de cholestérol total, et/ou de taux de triglycéride plasmatique tout en accroissant les niveaux de cholestérol à lipoprotéines de haute densité et permettant de retarder l'apparition de la rétinopathie diabétique chez un mammifère diabétique, un pré-diabétique ou non diabétique tout en minimisant des effets secondaires indésirables.
Jerling Markus
Wolff Andrew A.
Cv Therapeutics Inc.
Smart & Biggar
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