Method of treating disorders associated with protein kinase...

Details Method of treating disorders associated with protein kinase... Method of treating disorders associated with protein kinase...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 31/4375 (2006.01)

Patent

CA 2758974

The invention provides methods for the treatment or amelioration of disorders associated with undesired activity of protein kinase CK2, using compounds of Formula (I) that are potent, selective inhibitors of CK2, and pharmaceutical composi-tions of such compounds, wherein Z5, R6B, R6D, R8, n, R9 and p are defined as further described herein,

La présente invention concerne des méthodes de traitement ou d'amélioration de troubles liés à une activité non désirée de la protéine kinase CK2, au moyen de composés de formule (I) qui sont de puissants inhibiteurs sélectifs de la CK2. L'invention porte également sur des compositions pharmaceutiques desdits composés, Z5, R6B, R6D, R8, n, R9 et p étant tels que définis dans la description.

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