Method of treating malignancies

A - Human Necessities – 61 – K

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A61K 35/14 (2006.01) C12N 5/0783 (2010.01) A61K 31/704 (2006.01) A61K 33/24 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2288059

Use of a synergistic combination of chemotherapy and cell therapy with cells of a stable cell line characterized by non-MHC restricted cytotoxic activity in a method of treating tumors. The method of the invention permits reduced amounts of chemotherapeutic agents to be administered, resulting in a reduction of the side effects often associated therewith.

L'invention porte sur un procédé de traitement des tumeurs par combinaison synergique de chimiothérapie et d'une thérapie cellulaire utilisant des cellules de lignées de cellules stabilisées à activité cytotoxique non réduite par le CMH. Ladite méthode permet de réduire les doses d'agents chimiothérapeutiques à administrer et par là les effets secondaires souvent associés.

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