Method of treating mastitis and other staphylococcal infections

Details Method of treating mastitis and other staphylococcal infections Method of treating mastitis and other staphylococcal infections

A - Human Necessities

61

K

167/103.31, 167/

A61K 38/54 (2006.01) A61K 38/46 (2006.01)

Patent

CA 1330758

ABSTRACT OF THE DISCLOSURE Lysostaphin is used to eliminate and cure staphylo- coccal infections including the cure of mastitis by intra- mammary infusion. Administration of from 2 mg to 400 mg of lysostaphin to an infected bovine mammary gland eliminates staphylococci, and the reoccurrence common with antibiotic therapy is not observed. Teat-dips containing lysostaphin, mutanolysin and lysozyme can be used as a prophylactic. Synergistic enhancement of the killing effect of lysostaphin is observed when a mild surfactant or penicillin or both is included in the formulation.

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