Method of treating neurodegenerative disease

Details Method of treating neurodegenerative disease Method of treating neurodegenerative disease

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 31/7115 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2542232

Aspects featured in the invention relate to compositions and methods for inhibiting alpha-synuclein (SNCA) gene expression, such as for the treatment of neurodegenerative disorders. An anti- SNCA agent featured herein that targets the SNCA gene can have been modified to alter distribution in favor of neural cells.

Les aspects présentés dans cette invention concernent des compositions et des procédés d'inhibition de l'expression génique alpha-synucléine (SNCA), notamment utilisés dans le traitement de troubles neurodégénératifs. Un agent anti-SNCA présenté dans cette invention qui cible le gène SNCA peut avoir été modifié de manière à altérer la répartition en faveur des cellules neurales.

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