Method of treating ocular diseases by gene therapy

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/864 (2006.01) A61K 38/17 (2006.01) A61P 27/02 (2006.01) C12N 7/01 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2715875

A method for the treatment of diseases associated with mutations in ABCA4 gene by administering, to a subject in need thereof, an adeno-associated viral vector encoding an ABCR protein; genetic constructs and adeno-associated viral vectors for use in this method.

La présente invention a trait à un procédé de traitement d'affections associées à des mutations du gène ABCA4 grâce à l'administration à un sujet en ayant besoin d'un vecteur viral adénoassocié codant pour une protéine ABCR, ainsi qu'à des produits de recombinaison génétique et des vecteurs viraux adénoassociés utilisables dans le cadre du présent procédé.

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