A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/59 (2006.01) A61K 9/50 (2006.01) A61K 31/565 (2006.01) A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 33/06 (2006.01) A61K 33/16 (2006.01) A61K 33/22 (2006.01) A61K 33/24 (2006.01) A61K 38/23 (2006.01) A61K 39/08 (2006.01)
Patent
CA 2276465
Method of treating prostatic conditions such as prostate cancer and hyperplasia by administering 1.alpha.-hydroxyprevitamin D or activated vitamin D or a combination thereof in a sustained release form or a delayed and sustained release formulation. Both the sustained release form and the delayed, sustained release form deliver increase active vitamin D blood levels without significant risk of hypercalcemia associated with other oral dosing of vitamin D forms, to provide the beneficial effect to the diseased prostate tissue.
L'invention concerne une méthode de traitement de maladies prostatiques (comme le cancer de la prostate ou l'hyperplasie) par administration d'une 1 alpha-hydroxyprévitamine D et/ou d'une vitamine D activée, sous la forme d'une formulation à libération retardée ou d'une formulation à libération retardée et prolongée. Tant la formulation à libération retardée que la formulation à libération retardée prolongée apportent des taux sanguins accrus de vitamine D active, sans entraîner de risque important d'hypercalcémie associée à d'autres dosages oraux de préparations de vitamine D, et produisent les effets bénéfiques au tissu prostatique malade.
Bishop Charles W.
Knutson Joyce C.
Valliere Charles R.
Bone Care International Inc.
Shapiro Cohen
LandOfFree
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