Method of treating psychotic disorders

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 31/4439 (2006.01) A61P 25/18 (2006.01) C07D 209/14 (2006.01) C07D 209/46 (2006.01) C07D 209/48 (2006.01) C07D 239/00 (2006.01) C07D 277/00 (2006.01) C07D 403/08 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2373855

The invention relates to the use of compounds having both dopamine D2- antagonistic activity and serotonin reuptake inhibitory (SRI) activity for the treatment of psychotic disorders such as schizophrenia. The invention further relates to a group of novel (1, 2, 3,6-tetrahydropyridin-4-yl) indole and - furan derivatives having these activities.

L'invention concerne l'utilisation de composés présentant à la fois une activité antagoniste à la dopamine D2 et une activité inhibant le recaptage de la sérotonine (IRS) dans le traitement de troubles psychotiques tels que la schizophrénie. L'invention concerne également un groupe de nouveaux dérivés de (1,2,3,6-tétrahydropyridin-4-yl) indole et furane présentant ces activités.

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