Method of treating renal injury

Details Method of treating renal injury Method of treating renal injury

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 38/00 (2006.01) A61P 13/12 (2006.01) C07K 14/475 (2006.01) C07K 14/51 (2006.01)

Patent

CA 2446832

Herein is disclosed a mehtod of threating renal injury in a mammal, comprising administering to themammal a mixture of growth factors comprising at least two selected from bone morphogenic protein-2 (BMP-2), bon morphogenic protein-3 (BMP-3), bone morphogenic protein-4 (BMP-4), bone morphogenic protein-5 (BMP- 5), bone morphogenic protein-6 (BMP-6), bone morphogenic protein-7 (BMP-7), transforming growth factor .beta.beta (TGF-.beta.beta1, transforming growth factor .beta.beta(TGF-.beta.beta2, transforming growth factor .beta.beta3. (TGF-.beta.beta3, or fibroblast growth factor 1 (FGF-1)

L'invention concerne une méthode de traitement de lésions rénales chez un mammifère consistant à administrer audit mammifère un mélange de facteur de croissance contenant au moins deux éléments sélectionnés de la protéine-2 morphogénique de l'os (BMP-2), de la protéine-3 morphogénique de l'os (BMP-3), de la protéine-4 morphogénique de l'os (BMP-4), de la protéine-5 morphogénique de l'os (BMP-5), de la protéine-6 morphogénique (BMP-6), de la protéine-7 morphogénique de l'os (BMP-7), du facteur beta de croissance de transformation(TGF- beta 1), du facteur beta de croissance de transformation (TGF- beta 2), du facteur beta 3 de croissance de transformation (TGF- beta 3) ou du facteur 1 de croissance du fibroblaste (FGF-1).

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