Method of treating rhinitis or sinusitis

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01)

Patent

CA 2439631

The present invention is directed to methods of treating mucosal inflammation associated with rhinitis or sinusitis by administering peptidases that recognize and cleave polypeptides at Xaa-Pro sequences. In addition, the invention encompasses therapeutic packages in which pharmaceutical compositions containing the peptidases are preloaded in a device suitable for intranasally delivering drug.

La présente invention concerne des méthodes de traitement d'inflammations muqueuses associées à la rhinite ou à la sinusite par administration de peptidases qui reconnaissent et coupent des polypeptides au niveau de séquences Xaa-Pro. De plus, l'invention concerne des conditionnements thérapeutiques dans lesquels des compositions pharmaceutiques contenant lesdites peptidases sont préchargées dans un dispositif conçu pour délivrer un médicament de manière intranasale.

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