Method of treating sleep apnoea

A - Human Necessities – 61 – K

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Details

A61K 31/135 (2006.01) A61K 31/13 (2006.01) A61K 31/137 (2006.01) A61P 11/00 (2006.01) A61P 11/16 (2006.01) A61P 25/00 (2006.01) A61P 25/20 (2006.01)

Patent

CA 2367022

A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R1 and R2 are independently H or methyl, including individual enantiomers or racemates thereof, (for example <u>N</u>,<u>N</u>-dimethyl-1-[1- (4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride optionally in the form of its monohydrate) is used for treating sleeping disorders including sleep apnoea and snoring.

La présente invention concerne un composé représenté par la formule générale (I), ou l'un de ses sels pharmaceutiquement admis, convenant particulièrement pour le traitement de troubles du sommeil tels que l'apnée du sommeil et la ronchopathie. Dans cette formule, R¿1? et R¿2? sont indépendamment H ou méthyle, y-compris certains de leurs énantiomères ou racémiques, notamment l'hydrochlorure de <u>N</u>,<u>N</u>-diméthyl-1-[1-(4-chlorophényl)cyclobutyl]-3-méthylbutylamine, éventuellement sous sa forme monohydrate.

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