Method of treating viral infections with c-reactive protein

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2123786

The invention provides a method of treating a viral infection in a mammal comprising administering an effective amount of modified C-reactive protein (CRP) to the mammal. In particular, modified- CRP has been found to be effective and safe for treating retroviral infections, including human immunodeficiency virus 1. The invention also provides a method of neutralizing a virus comprising contacting the virus with modified-CRP. In particular, modified-CRP can be used to neutralize viruses in blood which is to be used for transfusions by adding the modified-CRP to the blood prior to the transfusion.

Procédé de traitement d'une infection virale chez un mammifère consistant à lui administrer une dose efficace de protéine C-réactive (CRP) modifiée. On a notamment découvert que la CRP modifiée est efficace et sans danger dans le traitement d'infections rétrovirales, y compris le virus 1 de l'immunodéficience humaine. L'invention concerne également un procédé de neutralisation d'un virus consistant à le mettre en contact avec la CRP modifiée. On peut notamment utiliser la CRP modifiée afin de neutraliser des virus dans le sang que l'on utilise dans des transfusions, par addition à ce dernier de la CRP modifiée avant la transfusion.

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