Method of treating vitamin b12 deficiency

A - Human Necessities – 61 – K

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Details

A61K 31/714 (2006.01) A61K 31/20 (2006.01) A61P 3/02 (2006.01)

Patent

CA 2704780

A method and composition for treating vitamin B12 deficiency in mammals that fail to respond to oral vitamin B12 therapy, including preparing a pharmaceutical composition for oral administration containing vitamin B12 and at least one substance selected from the group consisting of N-[8-(2-hydroxybenzoyl)amino]caprylic acid and its pharmaceutically acceptable salts, then administering the pharmaceutical composition to a subject to effectively treat the vitamin B12 deficiency.

La présente invention concerne un procédé et une composition destinés au traitement d'une carence en vitamine B12 chez des mammifères, ne réagissant pas à un traitement à base de vitamine B12 administré par voie orale. Ledit procédé comprend la préparation d'une composition pharmaceutique destinée à l'administration par voie orale et contenant de la vitamine B12 et au moins une substance choisie dans le groupe constitué de l'acide N-[8-(2-hydroxybenzoyl)amino]caprylique et de ses sels acceptables sur le plan pharmaceutique, puis l'administration de la composition pharmaceutique à un sujet en vue de pouvoir traiter avec efficacité une carence en vitamine B12.

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