Method of treatment and agents useful for same

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/70 (2006.01) A61K 31/4375 (2006.01) A61K 31/47 (2006.01) A61K 31/498 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 35/04 (2006.01) C07D 401/12 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2656825

The present invention relates generally to therapeutic agents, formulations comprising them and their use in the treatment, amelioration and/or prophylaxis of glioma brain tumours and related conditions. The therapeutic agent comprises two fused 6- membered rings with at least a nitrogren at position 1 and a hydroxyl at position 8.

La présente invention concerne, d'une manière générale, des agents thérapeutiques et des formulations comprenant lesdits agents, ainsi que leur utilisation dans le traitement, l'amélioration et/ou la prophylaxie des tumeurs cérébrales gliomes et des états apparentés. L'agent thérapeutique comprend deux cycles fusionnés à 6 éléments présentant au moins un azote à la position 1 et un hydroxyle à la position 8.

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