Method of treatment for lung diseases using antisense...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2223776

A method of treating airway disease in a subject in need of such treatment is disclosed. The method comprises topically administering to the subject an antisense oligonucleotide in an amount effective to treat the ariway disease, where the antisense oligonucleotide is essentially free of adenosine. Pharmaceutical formulations are also disclosed.

L'invention concerne un procédé de traitement de maladies des voies respiratoires chez un patient qui a besoin d'un tel traitement. Le procédé comprend l'administration topique au patient d'une quantité d'oligonucléotides antisens suffisante pour traiter la maladie des voies respiratoires, l'oligonucléotide antisens étant sensiblement exempt d'adénosine. L'invention concerne également des compositions pharmaceutiques.

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