Method of treatment of hormone-unresponsive metastatic...

Details Method of treatment of hormone-unresponsive metastatic... Method of treatment of hormone-unresponsive metastatic...

A - Human Necessities

61

K

A61K 33/24 (2006.01) A61K 31/13 (2006.01) A61K 31/138 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/513 (2006.01) A61K 31/535 (2006.01) A61K 31/5375 (2006.01) A61K 31/675 (2006.01) A61K 31/704 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2179377

Prostate cancer particularly hormone-unresponsive metastatic prostate cancer, is treated by cyclophosphamide or other normally substantially inactive agent. Potentiation of the anti-cancer activity and amelioration of cyclophosphamide-associated toxicity is achieved by an initial intravenous infusion of DPPE over an approximately one hour period prior to cyclophosphamide treatment.

Le cancer de la prostate, particulièrement le cancer de la prostate métastatique ne réagissant pas aux hormones, est traité par cyclophosphamides ou tout autre agent normalement inactif. La potentialisation de l'activité anticancéreuse et l'amélioration de la toxicité associée aux cyclophosphamides sont assurées par une injection intraveineuse initiale de DPPE par perfusion pendant environ une heure avant le traitement par les cyclophosphamides.

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