Method of treatment or management of stress

Details Method of treatment or management of stress Method of treatment or management of stress

A - Human Necessities

61

K

A61K 36/00 (2006.01)

Patent

CA 2616602

The present invention provides a method of treatment or management of various adaptogenic conditions, such as, stress in mammals, more particularly, humans, comprising administering Withania somnifera plant extract. A high purity extract composition comprising withanolide glycosides, oligosaccharides, withanolide aglycones and a minimum level of polysaccharides, and a pharmaceutically, veterinary or nutritionally acceptable carrier(s) is disclosed. Preferably, the composition of the present invention can be devoid of any alkaloids or contains trace levels of alkaloids. The method of treatment or management of stress administering the composition comprising Withania somnifera of the present invention does not suffer from any one of the abovementioned side effects even after prolonged use. A method of preconditioning a mammalian patient to improve the patient's resistance and reaction to subsequently encountered stress is described.

L'invention concerne une méthode de traitement ou de gestion de troubles adaptogéniques variés, notamment le stress chez les mammifères, en particulier chez les humains. Cette méthode consiste à administrer un extrait végétal de Withania somnifera. L'invention concerne une composition d'extrait de haute pureté comprenant des glycosides de withanolides, des oligosaccharides, des aglycones de withanolides et une teneur minimale en polysaccharides, et au moins un vecteur pharmaceutiquement, vétérinairement ou nutritionnellement acceptable. De préférence, la composition de l'invention est dépourvue d'alcaloïdes, ou contient des alcaloïdes sous forme de trace. La méthode de traitement ou de gestion de stress de l'invention qui consiste à administrer la composition susmentionnée comprenant du Withania somnifera ne présente pas d'effets secondaires, même après une utilisation prolongée. L'invention concerne une méthode de préconditionnement d'un patient mammifère permettant d'améliorer la résistance du patient et sa réaction à un stress ultérieurement subi.

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