Method of treatment or prophylaxis inflammatory pain

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/395 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2646379

This invention discloses the use of angiotensin II receptor 2 (AT2 receptor) antagonists for the treatment, prophylaxis, reversal and/or symptomatic relief of inflammatory pain, including hyperalgesia, thermal or mechanical allodynia, in vertebrate animals and particularly in human subjects. The AT2 receptor antagonists may be provided alone or in combination with other compounds such as those that are useful in the control of inflammatory conditions.

La présente invention concerne l'utilisation d'antagonistes du récepteur 2 de l'angiotensine II (récepteur AT2) dans le traitement, la prophylaxie, l'inversion et/ou le soulagement des symptômes d'une douleur inflammatoire, y compris l'hyperalgésie, l'allodynie thermique ou mécanique, chez des animaux vertébrés, et en particulier chez l'homme. Les antagonistes du récepteur AT2 peuvent se présenter seuls ou en combinaison avec d'autres composés tels que ceux qui sont employés dans la gestion d'états inflammatoires.

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