Method of use of epiregulin protein and nucleic acid...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) A61K 38/18 (2006.01) A61P 29/00 (2006.01) G01N 33/68 (2006.01) C07K 14/485 (2006.01)

Patent

CA 2669933

The present invention relates to nucleotide and protein sequences of epiregulin and epiregulin like proteins and nucleotides and methods employing them as a drug response marker in inflammatory conditions. The invention also provides epiregulin protein for treatment of inflammatory conditions like psoriasis and rheumatoid arthritis alone or in combination with one or more anti-inflammatory compounds.

La présente invention porte sur des séquences nucléotidiques et de protéine de l'épiréguline et sur des protéines et nucléotides analogues à l'épiréguline et sur des procédés les employant comme marqueur au médicament dans des conditions inflammatoires. L'invention propose également une protéine d'épiréguline pour le traitement de conditions inflammatoires comme le psoriasis et l'arthrite rhumatoïde individuellement ou en combinaison avec un ou plusieurs composés anti-inflammatoires.

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