Method of using bar1 for secreting foreign proteins

Details Method of using bar1 for secreting foreign proteins Method of using bar1 for secreting foreign proteins

C - Chemistry, Metallurgy

12

N

150/15, 195/1.2,

C12N 15/80 (2006.01) C07K 14/62 (2006.01) C12N 1/15 (2006.01) C12N 9/60 (2006.01) C12N 15/62 (2006.01) C12N 15/81 (2006.01)

Patent

CA 1316133

ABSTRACT A method is provided for producing a foreign protein in a host organism whereby the protein is processed through the secretory pathway of the host. Production and processing is achieved by transforming the host organism with a vector comprising at least the signal peptide coding region of the yeast S. cerevisiae BAR1 gene fused to a foreign structural gene. DNA constructs and transformants are also provided containing a region of the BAR1 gene encoding the signal peptide and a KEX2 processing site, and a foreign structural gene. In particular, proinsulin is expressed and secreted from Schizosaccharomyces pombe and Saccharomyces cerevisiae.

521206

Affiliated with

Also associated with

Rating

Method of using bar1 for secreting foreign proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of using bar1 for secreting foreign proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of using bar1 for secreting foreign proteins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1196009